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Article

Val/Leu247 and Trp/Ser316 polymorphisms in beta 2 glycoprotein I and their association with thrombosis in unselected Chilean patients.

Clinical rheumatology - 1 Mar 2007

Palomo Iván, Pereira Jaime, Alarcón Marcelo, Vásquez Marcela, Pinochet Carmen, Poblete Fernando, Mendez Evelyn, Sandoval Jeannette, Vidal Rolando, Pierangeli Silvia

Abstract excerpt

It is known that polymorphisms of beta (2)-glycoprotein I (beta (2)GPI) in exon 7 affect interaction between the phospholipid binding site and the antibodies, and that other polymorphisms in exon 8 increase the generation of antibodies. In this study, we analyzed genetic polymorphisms of beta (2)GPI in unselected Chilean patients to determine the prevalence of beta (2)GPI polymorphisms in the phospholipid domain...

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Source

Identifiers

PMID: 16724168
DOI: 10.1007/s10067-006-0289-z

Genes

GPI

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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