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Article

A functional SNP of the Interleukin-18 gene is associated with the presence of hepatocellular carcinoma in hepatitis B virus-infected patients.

Digestive diseases and sciences - 1 Dec 2009

Kim Yong Seok, Cheong Jae Youn, Cho Sung Won, Lee Kee Myung, Hwang Jae Chul, Oh Bermseok, Kimm Kuchan, Lee Jung A, Park Byung Lae, Cheong Hyun Sub, Shin Hyoung Doo, Kim Jin Hong

Abstract excerpt

BACKGROUND/AIM: The natural course of hepatitis B virus (HBV) infection is likely related to host immune factors. Interleukin-18 (IL-18) plays a significant role in immune defense. This study was undertaken to determine the association between the presence of hepatocellular carcinoma (HCC) and single-nucleotide polymorphisms (SNPs) in the IL-18 gene in HBV-infected patients. METHODS: Between March 2002 and...

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Identifiers

PMID: 19757044
DOI: 10.1007/s10620-009-0970-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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