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Article

Recombination or heterogeneity: is there a second locus for adult polycystic kidney disease?

Journal of medical genetics - 1 Jul 1990

Elles R G, Read A P, Hodgkinson K A, Watters A, Harris R

Abstract excerpt

Twenty-four families with adult onset polycystic kidney disease were typed for markers flanking the PKD1 locus on chromosome 16. The aggregated results gave a significant lod score in favour of linkage to PKD1. Within this group of families two showed unusual features: recombinations, including double recombinations, and, in one family, an unexpectedly high proportion of affected people. We consider the evidence...

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Source

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Identifiers

PMID: 1975629
DOI: 10.1136/jmg.27.7.413
PMCID: PMC1017176

Genes

PKD1
PKD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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