Article
Linkage disequilibrium in the region of the autosomal dominant polycystic kidney disease gene (PKD1).
American journal of human genetics - 1 Aug 1994
Snarey A, Thomas S, Schneider M C, Pound S E, Barton N, Wright A F, Somlo S, Germino G G, Harris P C, Reeders S T
Abstract excerpt
The gene for autosomal dominant polycystic kidney disease (PKD1) is located on chromosome 16p, between the flanking markers D16S84 and D16S125 (26.6prox). This region is 750 kb long and has been cloned. We have looked at the association of 10 polymorphic markers from the region, with the disease...
Topics
- Alleles
- Base Sequence
- Chi-Square Distribution
- Chromosome Mapping
- Chromosomes, Human, Pair 16
- DNA Primers
- DNA, Satellite
- DNA, Single-Stranded
- Female
- Gene Frequency
- Genetic Markers
- Haplotypes
- Humans
- Linkage Disequilibrium