Article
Fractalkine receptor polymorphisms V2491 and T280M as genetic risk factors for restenosis.
Thrombosis and haemostasis - 1 Dec 2005
Niessner Alexander, Marculescu Rodrig, Kvakan Heda, Haschemi Arvand, Endler Georg, Weyand Cornelia M, Maurer Gerald, Mannhalter Christine, Wojta Johann, Wagner Oswald, Huber Kurt
Abstract excerpt
The chemokine fractalkine (FKN) recruits leukocytes into lesions of the arterial wall, which may lead to restenosis after stenting. FKN also regulates proliferation of smooth muscle cells, another mechanism pivotal to neointimal thickening. We assessed the hypothesis that functionally important polymorphisms of the FKN receptor CX3CR1 influence restenosis after coronary stenting. Three hundred and sixty-five...
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