Article
Effects of polymorphisms in chemokine ligands and receptors on susceptibility to coronary artery disease.
Thrombosis research - 1 Jan 2007
Apostolakis Stavros, Baritaki Stavroula, Kochiadakis Georgios E, Igoumenidis Nikolaos E, Panutsopulos Dimitrios, Spandidos Demetrios A
Abstract excerpt
INTRODUCTION: Atherosclerosis, the underlying disorder of coronary artery disease (CAD), is an inflammatory process involving multiple molecular pathways. Chemokine-mediated mechanisms are potent regulators of atherosclerosis. Genetic variations that alter such signaling pathways could affect susceptibility to CAD. We investigated the effect of 5 common variations of chemokine and chemokine receptor genes...
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