Article
Frequent and significant K-ras mutation in the pancreas, the bile duct, and the gallbladder in autoimmune pancreatitis.
Pancreas - 1 Nov 2009
Kamisawa Terumi, Tsuruta Kouji, Okamoto Atsutake, Horiguchi Shin-ichirou, Hayashi Yukiko, Yun Xiaoqing, Yamaguchi Toshikazu, Sasaki Tsuneo
Abstract excerpt
OBJECTIVES: To assess the relationship between autoimmune pancreatitis (AIP) and pancreatic cancer, we analyzed K-ras mutation in the pancreatobiliary tissues of patients with AIP. METHODS: An analysis of K-ras mutation and an immunohistochemical study were performed on the pancreas of 8 patients with AIP and 10 patients with chronic alcoholic pancreatitis and on the common bile duct and the gallbladder of 9...
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