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Article

Methylation of Tumor Suppressor Genes in Autoimmune Pancreatitis.

Pancreas - 1 Jan 2000

Kinugawa Yasuhiro, Uehara Takeshi, Sano Kenji, Matsuda Kazuyuki, Maruyama Yasuhiro, Kobayashi Yukihiro, Nakajima Tomoyuki, Hamano Hideaki, Kawa Shigeyuki, Higuchi Kayoko, Hosaka Noriko, Shiozawa Satoshi, Ishigame Hiroki, Ota Hiroyoshi

Abstract excerpt

OBJECTIVES: Autoimmune pancreatitis (AIP) is a representative IgG4-related and inflammatory disease of unknown etiology. To clarify mechanisms of carcinogenesis resulting from AIP, we focused on methylation abnormalities and KRAS mutations in AIP. METHODS: Six tumor suppressor genes (NPTX2, Cyclin D2, FOXE1, TFPI2, ppENK, and p16) that exhibited hypermethylation in pancreatic carcinoma were selected for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28196014
DOI: 10.1097/MPA.0000000000000804

Genes

AIP
KRAS
TFPI2
FOXE1
NPTX2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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