Transforming growth factor type beta 1 modulates the effects of basic fibroblast growth factor on growth and phenotypic expression of rat astroblasts in vitro.

doi:10.1002/jcp.1041440315

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Article

Transforming growth factor type beta 1 modulates the effects of basic fibroblast growth factor on growth and phenotypic expression of rat astroblasts in vitro.

Journal of cellular physiology - 1 Sept 1990

Labourdette G, Janet T, Laeng P, Perraud F, Lawrence D, Pettmann B

Abstract excerpt

In a search of the growth factors possibly involved in brain ontogenesis we have examined the effects of transforming growth factor beta 1 (TGF-beta 1) on the growth and phenotypic expression of rat astroblasts in primary culture. Along TGF-beta 1 elicited only a slight negative effect on the growth of these cells. However, this factor was found to modulate the mitogenic effects of other growth factors. On...

Topics

Animals
Astrocytes
Bromodeoxyuridine
Cell Division
Dose-Response Relationship, Drug
Fibroblast Growth Factors
Gene Expression Regulation
Glutamate-Ammonia Ligase
Kinetics
Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Proto-Oncogene Proteins

Proto-Oncogene Proteins c-fos

Proto-Oncogene Proteins c-myc

Rats

Stem Cells

Time Factors

Transforming Growth Factors

Source

Open in PubMed

Identifiers

PMID: 1975257
DOI: 10.1002/jcp.1041440315

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1975257-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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