Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Transforming growth factor type beta 1 modulates the effects of basic fibroblast growth factor on growth and phenotypic expression of rat astroblasts in vitro.

Journal of cellular physiology - 1 Sept 1990

Labourdette G, Janet T, Laeng P, Perraud F, Lawrence D, Pettmann B

Abstract excerpt

In a search of the growth factors possibly involved in brain ontogenesis we have examined the effects of transforming growth factor beta 1 (TGF-beta 1) on the growth and phenotypic expression of rat astroblasts in primary culture. Along TGF-beta 1 elicited only a slight negative effect on the growth of these cells. However, this factor was found to modulate the mitogenic effects of other growth factors. On...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Division
Share to Dose-Response Relationship, Drug

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Expression Regulation

Share to Kinetics

Share to Phenotype

Share to Proto-Oncogene Proteins

Share to Time Factors

Source

Identifiers

PMID: 1975257
DOI: 10.1002/jcp.1041440315

Genes

EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Transforming growth factor type beta 1 modulates the effects of basic fibroblast growth factor on growth and phenotypic expression of rat astroblasts in vitro.PMID 1975257Read ↗

Basic fibroblast growth factor priming increases the responsiveness of immortalized hypothalamic luteinizing hormone releasing hormone neurones to neurotrophic factors.Semantic proximity Read ↗

In human fetal astrocytes exposure to interleukin-1 beta stimulates acquisition of the GD3+ phenotype and inhibits cell division.Semantic proximity Read ↗

Phenotypic alteration of astrocytes induced by ciliary neurotrophic factor in the intact adult brain, As revealed by adenovirus-mediated gene transfer.Semantic proximity Read ↗

Bone morphogenetic proteins inhibit proliferation, induce reversible differentiation and prevent cell death in astrocyte lineage cells.Semantic proximity Read ↗

Rat cerebral cortical neurons in primary culture release a mitogen specific for early (GD3+/04-) oligodendroglial progenitors.Semantic proximity Read ↗

Phenotypic transformation of normal rat kidney cells by transforming growth factor beta is not paralleled by enhanced production of a platelet-derived growth factor.Semantic proximity Read ↗

Rapid TGFβ1 effects on actin cytoskeleton of astrocytes: Comparison with other factors and implications for cell motilitySemantic proximity Read ↗

Transforming growth factor beta1 may directly influence gonadotropin-releasing hormone gene expression in the rat hypothalamus.Semantic proximity Read ↗

Effects of transforming growth factor-beta 1 on growth of aortic smooth muscle cells. Influences of interaction with growth factors, cell state, cell phenotype, and cell cycle.Semantic proximity Read ↗

Stimulation of C2C12 myoblast growth by basic fibroblast growth factor and insulin-like growth factor 1 can occur via mitogen-activated protein kinase-dependent and -independent pathways.Semantic proximity Read ↗

Platelet activating factor, an endogenous mediator of inflammation, induces phenotypic transformation of rat embryo cells.Semantic proximity Read ↗

Insulin‐like growth factor‐I increases astrocyte intercellular gap junctional communication and connexin43 expression in vitroSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.