Article
Fimbrial phase variation in Bordetella pertussis: a novel mechanism for transcriptional regulation.
The EMBO journal - 1 Sept 1990
Willems R, Paul A, van der Heide H G, ter Avest A R, Mooi F R
Abstract excerpt
Fimbriae belong to a class of extracellular filamentous proteins which are involved in the attachment of bacteria to host tissues. Bordetella pertussis, the etiological agent of whooping cough, produces two serologically distinct fimbriae. We show that, like a number of other B. pertussis virulence genes, transcription of the fimbrial subunit genes (fim) is positively controlled by trans-acting polypeptides...
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