Immunosuppression in murine renal cell carcinoma. II. Identification of responsible lymphoid cell phenotypes and examination of elimination of suppression.

doi:10.1007/BF01741404

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Article

Immunosuppression in murine renal cell carcinoma. II. Identification of responsible lymphoid cell phenotypes and examination of elimination of suppression.

Cancer immunology, immunotherapy : CII - 1 Jan 1990

Gregorian S K, Battisto J R

Abstract excerpt

In our companion paper we have reported that cell-mediated immunity of mice bearing renal cell carcinoma is profoundly suppressed. The non-responsiveness of such animals was found to be attributable to Renca cells themselves and to splenic lymphoid cells that down-regulate other fully capable lymphoid cells. In this communication the lymphoid cell source of suppression within Renca-bearing mice has been explored...

Topics

Animals
Antigens, Surface
Carcinoma, Renal Cell
Dinoprostone
Female
Immune Tolerance
Indomethacin
Kidney Neoplasms
Killer Cells, Lymphokine-Activated
Killer Cells, Natural
Lymphocytes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice

Mice, Inbred BALB C

Phenotype

Radiation Tolerance

T-Lymphocytes, Regulatory

Thy-1 Antigens

Source

Open in PubMed Open full text

Identifiers

PMID: 1974826
DOI: 10.1007/BF01741404
PMCID: PMC11038562

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1974826-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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