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Article

A pooled investigation of Toll-like receptor gene variants and risk of non-Hodgkin lymphoma.

Carcinogenesis - 1 Feb 2009

Purdue Mark P, Lan Qing, Wang Sophia S, Kricker Anne, Menashe Idan, Zheng Tong-Zhang, Hartge Patricia, Grulich Andrew E, Zhang Yawei, Morton Lindsay M, Vajdic Claire M, Holford Theodore R, Severson Richard K, Leaderer Brian P, Cerhan James R, Yeager Meredith, Cozen Wendy, Jacobs Kevin, Davis Scott, Rothman Nathaniel, Chanock Stephen J, Chatterjee Nilanjan, Armstrong Bruce K

Abstract excerpt

Toll-like receptors (TLRs) may influence the development of non-Hodgkin lymphoma (NHL) given their important roles in recognizing microbial pathogens and stimulating multiple immune pathways. We conducted an investigation of TLR gene variants in a pooled analysis including three population-based case-control studies of NHL (1946 cases and 1808 controls). Thirty-six tag single-nucleotide polymorphisms (SNPs) in...

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Identifiers

PMID: 19029192
DOI: 10.1093/carcin/bgn262
PMCID: PMC2639046

Genes

TLR1
TLR10
TLR2
TLR6
TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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