Article
The circling behavior of the deafblind LEW-ci2 rat is linked to a segment of RNO10 containing Myo15 and Kcnj12.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Sept 2003
Chwalisz Wojciech T, Koelsch Bernd U, Kindler-Röhrborn Andrea, Hedrich Hans J, Wedekind Dirk
Abstract excerpt
The LEW/Ztm-ci2 rat is an autosomal recessive mutant that displays circling behavior, deafness, progressive retinopathy, locomotor hyperactivity, ataxia, and opisthotonus. We performed a genome-wide scan of a (LEW/Ztm-ci2 x BN/Ztm) F1 x LEW/Ztm-ci2 backcross population with anonymous microsatelli...
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