Article
The polymorphic human DNA sequence D8S8 assigned to 8q13-21.1, close to the carbonic anhydrase gene cluster, by isotopic and nonisotopic in situ hybridization and by linkage analysis.
Annals of human genetics - 1 May 1990
Edwards Y, Williams S, West L, Lipowicz S, Sheer D, Attwood J, Spurr N, Sarkar R, Saha N, Povey S
Abstract excerpt
Restriction fragment length polymorphism at the D8S8 locus is explained by the occurrence of at least two alternative alleles at two separate TaqI sites; TaqI-A allele frequencies 0.73 and 0.27 and TaqI-B allele frequencies 0.94 and 0.06. The D8S8 locus has been assigned to 8q13-21.1, near to the...
Topics
- Alleles
- Base Sequence
- Carbonic Anhydrases
- Chromosome Mapping
- Chromosomes, Human, Pair 8
- DNA
- Fluorescent Antibody Technique
- Genetic Linkage
- Haplotypes
- Humans
- Lod Score
- Multigene Family
- Nucleic Acid Hybridization
- Phenotype