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Article

Dinucleotide polymorphism at the DXS1178 locus is tightly linked to PGK1 at Xq13.

Human genetics - 1 Apr 1995

Fujita R, Skolnick C, Pakstis A J, Yang-Feng T L, Swaroop A

Abstract excerpt

A polymorphic CA repeat (locus name DXS1178) was isolated from a 1-megabase YAC (OTCC) containing the OTC gene, located at Xp21.1. However, amplification in human-rodent hybrid cells and segregation analysis in three CEPH families mapped the DXS1178 locus at Xq13. The mapping ambiguity is apparently caused by the chimeric nature of the OTCC YAC clone.

Topics

Alleles
Animals
Base Sequence
Chromosome Mapping
Chromosomes, Artificial, Yeast
DNA Primers
Humans
Mice
Molecular Sequence Data
Ornithine Carbamoyltransferase
Phosphoglycerate Kinase
Polymerase Chain Reaction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Genetic

Repetitive Sequences, Nucleic Acid

Retinitis Pigmentosa

X Chromosome

Source

Identifiers

PMID: 7705848
DOI: 10.1007/BF00208981

Genes

OTC
PGK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7705848-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Click a neighbor to travelStep 1 · 12 closest

Dinucleotide polymorphism at the DXS1178 locus is tightly linked to PGK1 at Xq13.PMID 7705848Read ↗

YAC/STS map of 15Mb of Xp21.3-p11.3, at 100kb resolution, with refined comparisons of genetic distances and DMD structure.Semantic proximity Read ↗

The gene for Aarskog syndrome is located between DXS255 and DXS566 (Xp11.2-Xq13).Semantic proximity Read ↗

Isolation and characterization of a highly polymorphic human locus (DXS455) in proximal Xq28.Semantic proximity Read ↗

Homologous loci DXYS156X and DXYS156Y contain a polymorphic pentanucleotide repeat (TAAAA)n and map to human X and Y chromosomes.Semantic proximity Read ↗

X-linked dyskeratosis congenita is caused by mutations in a highly conserved gene with putative nucleolar functions.Semantic proximity Read ↗

Physical and transcriptional mapping of the X-linked cleft palate and ankyloglossia (CPX) critical region.Semantic proximity Read ↗

DXS106 and DXS559 flank the X-linked dystonia-parkinsonism syndrome locus (DYT3).Semantic proximity Read ↗

Dinucleotide repeat polymorphism within the PHKA1 gene at Xq12-q13.Semantic proximity Read ↗

Identification of new markers in Xp21 between DXS28 (C7) and DMD.Semantic proximity Read ↗

Four STR polymorphisms map to a 500 kb region between DXS15 and DXS134.Semantic proximity Read ↗

Isolation and characterization of three microsatellite markers in the proximal long arm of the human X chromosome.Semantic proximity Read ↗

A high-density single-nucleotide polymorphism map of Xq25-q28.Semantic proximity Read ↗

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