Article
Three DNA markers for hypophosphataemic rickets.
Human genetics - 1 Jul 1992
Rowe P S, Read A P, Mountford R, Benham F, Kruse T A, Camerino G, Davies K E, O'Riordan J L
Abstract excerpt
This paper presents three markers, 16D/E, pHMAI (DXS208), and CRI-L1391 (DXS274), that show close linkage for X-linked hypophosphataemic rickets (HYP). DXS274 is closely linked to HYP (theta max = 0.00, Zmax = 4.20), and DXS41 (99.6), (theta max = 0.00, Zmax = 5.20). Marker 16D/E maps distal to the disease locus (theta max = 0.05, Zmax = 3.11). The pHMAI probe recognises the same restriction fragment length...
Topics
- Blotting, Southern
- Chromosome Aberrations
- Female
- Genetic Linkage
- Genetic Markers
- Genetic Variation
- Humans
- Hypophosphatemia, Familial
- Lod Score
- Male
- Polymorphism, Restriction Fragment Length