Article
Genetic diversity and evolution of human metapneumovirus fusion protein over twenty years.
Virology journal - 9 Sept 2009
Yang Chin-Fen, Wang Chiaoyin K, Tollefson Sharon J, Piyaratna Rohith, Lintao Linda D, Chu Marla, Liem Alexis, Mark Mary, Spaete Richard R, Crowe James E, Williams John V
Abstract excerpt
BACKGROUND: Human metapneumovirus (HMPV) is an important cause of acute respiratory illness in children. We examined the diversity and molecular evolution of HMPV using 85 full-length F (fusion) gene sequences collected over a 20-year period. RESULTS: The F gene sequences fell into two major groups, each with two subgroups, which exhibited a mean of 96% identity by predicted amino acid sequences. Amino acid...
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