Article
Limited inter- and intra-patient sequence diversity of the genetic lineage A human metapneumovirus fusion gene.
Virus genes - 1 Aug 2005
Winther Thilde Nordmann, Madsen Chris D, Pedersen Anders G, von Linstow Marie-Louise, Eugen-Olsen Jesper, Hogh Birthe
Abstract excerpt
Human metapneumovirus (hMPV) is associated with respiratory tract illness especially in young children. Two hMPV genetic lineages, A and B, and four sublineages A1, A2 and B1, B2 have been defined. Infection with hMPV occurs through membrane fusion mediated by the hMPV fusion (F) protein. In this study, the inter- and intra-patient genetic diversity of the lineage A hMPV F gene was investigated. Ten isolates were...
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