Article
Genetic diversity and molecular evolution of the major human metapneumovirus surface glycoproteins over a decade.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Nov 2013
Papenburg Jesse, Carbonneau Julie, Isabel Sandra, Bergeron Michel G, Williams John V, De Serres Gaston, Hamelin Marie-Ève, Boivin Guy
Abstract excerpt
BACKGROUND: Human metapneumovirus (HMPV) is a recently discovered paramyxovirus that is a major cause of respiratory infections worldwide. OBJECTIVES: We aim to describe the molecular evolution of the HMPV F (fusion) and G (attachment) surface glycoproteins because they are targets for vaccines, monoclonal antibodies and antivirals currently in development. STUDY SETTING: Nasopharyngeal aspirates were collected...
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