A nonsynonymous gene variant in the adiponutrin gene is associated with nonalcoholic fatty liver disease severity.

doi:10.1194/jlr.P900013-JLR200

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Article

A nonsynonymous gene variant in the adiponutrin gene is associated with nonalcoholic fatty liver disease severity.

Journal of lipid research - 1 Oct 2009

Sookoian Silvia, Castaño Gustavo O, Burgueño Adriana L, Gianotti Tomas Fernández, Rosselli María Soledad, Pirola Carlos Jose

Abstract excerpt

We explored the role of the adiponutrin (PNPLA3) nonsynonymous-rs738409 single nucleotide polymorphism (SNP) in genetic susceptibility to nonalcoholic fatty liver disease (NAFLD) and whether this SNP contributes to the severity of histological disease. Two hundred sixty-six individuals were evaluated in a case-control association study, which included 172 patients with features of NAFLD and 94 control subjects....

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Identifiers

PMID: 19738004
DOI: 10.1194/jlr.P900013-JLR200
PMCID: PMC2739750

Genes

PNPLA3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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A nonsynonymous gene variant in the adiponutrin gene is associated with nonalcoholic fatty liver disease severity.PMID 19738004Read ↗

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