Article
Crlz1 activates transcription by mobilizing cytoplasmic CBFbeta into the nucleus.
Biochimica et biophysica acta - 1 Jan 2000
Park Sung-Kyun, Lim Jung-Hyun, Kang Chang-Joong
Abstract excerpt
Transcriptional function of a novel Crlz1 protein was examined by using the CBF site-containing IgJ enhancer, because it was originally cloned due to its ability to bind CBFbeta, a subunit of CBF heterodimer, of which Runx is the other subunit. In a cotransfection experiment, Crlz1 was shown to i...
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