Article
Heat-shock protein 70 gene polymorphism is associated with the severity of diabetic foot ulcer and the outcome of surgical treatment.
The British journal of surgery - 1 Oct 2009
Mir K A, Pugazhendhi S, Paul M J, Nair A, Ramakrishna B S
Abstract excerpt
BACKGROUND: Foot ulcer is a significant cause of morbidity in diabetics. Genetic make-up can determine inflammatory and healing responses. This study examined the hypothesis that specific polymorphisms of the heat-shock protein 70 gene could predispose to the severity of diabetic foot ulceration. METHODS: Some 106 consecutive diabetic patients (101 evaluable) with foot ulceration admitted to a tertiary care...
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