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Article

Single nucleotide polymorphisms in cytokine/chemokine genes are associated with severe infection, ulcer grade and amputation in diabetic foot ulcer.

International journal of biological macromolecules - 15 Oct 2018

Viswanathan Vijay, Dhamodharan Umapathy, Srinivasan Valarmathi, Rajaram Rama, Aravindhan Vivekanandhan

Abstract excerpt

Compared to other complications the genetics of diabetic foot ulcer is poorly studied. The Interleukin (IL)-6 (-174G > C/rs1800795), Tumor Necrosis Factor (TNF)-α (-308G > A/rs1800629) and (-238G > A/rs361525) and Stromal cell Derived Factor (SDF)-1 (+801G > A/rs1801157) are well characterized single nucleotide polymorphisms (SNPs) which were previously shown to be associated with Diabetic Foot Ulcer (DFU). In...

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Identifiers

PMID: 30009916
DOI: 10.1016/j.ijbiomac.2018.07.083

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TNF
CRP

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