Article
Loss of responses to visual but not electrical stimulation in ganglion cells of rats with severe photoreceptor degeneration.
Journal of neurophysiology - 1 Dec 2009
Sekirnjak Chris, Hulse Clare, Jepson Lauren H, Hottowy Pawel, Sher Alexander, Dabrowski Wladyslaw, Litke A M, Chichilnisky E J
Abstract excerpt
Retinal implants are intended to help patients with degenerative conditions by electrically stimulating surviving cells to produce artificial vision. However, little is known about how individual retinal ganglion cells respond to direct electrical stimulation in degenerating retina. Here we used a transgenic rat model to characterize ganglion cell responses to light and electrical stimulation during photoreceptor...
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