Article
Characterization of tumor-derived pancreatic stellate cells.
The Journal of surgical research - 1 Nov 2009
Farrow Buckminster, Rowley David, Dang Truong, Berger David H
Abstract excerpt
BACKGROUND: Pancreatic stellate cells (PSCs) are key mediators of the desmoplastic reaction that characterizes pancreatic adenocarcinoma. We sought to isolate and characterize tumor-derived pancreatic stellate (TDPS) cells to further understand how these stromal cells influence pancreatic cancer behavior. METHODS: We established a stable line of non-immortalized PSCs from a patient with pancreatic adenocarcinoma...
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