Article
Inflammation and pancreatic cancer: disease promoter and new therapeutic target.
Journal of gastroenterology - 1 Apr 2014
Hamada Shin, Masamune Atsushi, Shimosegawa Tooru
Abstract excerpt
Chronic inflammation has a certain impact on the carcinogenesis of the digestive organs. The characteristic tissue structure of pancreatic cancer, desmoplasia, results from inflammatory processes induced by cancer cells and stromal cells. Concerning the progression of pancreatic cancer, recent research has clarified the pivotal role of tumor-stromal interaction, which promotes the development of an invasive...
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