Article
Morphology and myofiber composition of skeletal musculature of the forelimb in young and aged wild type and myostatin null mice.
Rejuvenation research - 1 Aug 2009
Elashry Mohamed I, Otto Anthony, Matsakas Antonios, El-Morsy Salah E, Patel Ketan
Abstract excerpt
Most current research into therapeutic approaches to muscle diseases involves the use of the mouse as an experimental model. Furthermore, a major strategy to alleviate myopathic symptoms through enhancing muscle growth and regeneration is to inhibit the action of myostatin (Mstn), a transforming growth factor-beta (TGF-beta) family member that inhibits muscle growth. Presently, however, no study has expanded the...
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