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Article

Computational design, synthesis, and evaluation of miniproteins as androgen receptor coactivator mimics.

Chemical communications (Cambridge, England) - 28 Sept 2009

Vaz Belen, Möcklinghoff Sabine, Folkertsma Simon, Lusher Scott, de Vlieg Jacob, Brunsveld Luc

Abstract excerpt

Insertion of 3 to 4 mutations, based on in silico modelling, in a diverse set of natural miniproteins generates potent androgen receptor (AR) binders and a clear insight into the structure-activity relationship of such coactivator mimics concerning helix length.

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Share to Androgens
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19724790
DOI: 10.1039/b910677d

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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