Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

RNA splicing factors regulated by HPV16 during cervical tumour progression

4 Aug 2009

Abstract excerpt

The most prevalent human papillomaviruses (HPVs) causing cervical disease are the 'high-risk' HPV types 16 and 18. All papillomaviruses express a transcription factor, E2, that can regulate viral and cellular gene expression. Recently, we demonstrated high-risk HPV E2-mediated transcriptional transactivation of SF2/ASF. This essential oncoprotein is a key member of a family of proteins, the SR proteins, that...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related molecular mechanisms research
Share to Cervical Cancer and HPV Research
Share to T-cell and Retrovirus Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 19718710
DOI: 10.1002/path.2608

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

RNA splicing factors regulated by HPV16 during cervical tumour progressionPMID 19718710Read ↗

Human Papillomavirus E2 Regulates SRSF3 (SRp20) To Promote Capsid Protein Expression in Infected Differentiated KeratinocytesSemantic proximity Read ↗

Human Papillomavirus Type 16 E2 Protein Transcriptionally Activates the Promoter of a Key Cellular Splicing Factor, SF2/ASFSemantic proximity Read ↗

Human Papillomavirus 16 Oncoprotein Expression Is Controlled by the Cellular Splicing Factor SRSF2 (SC35)Semantic proximity Read ↗

Multiple ASF/SF2 Sites in the Human Papillomavirus Type 16 (HPV-16) E4-Coding Region Promote Splicing to the Most Commonly Used 3′-Splice Site on the HPV-16 GenomeSemantic proximity Read ↗

The alternative splicing factor hnRNP A1 is up-regulated during virus-infected epithelial cell differentiation and binds the human papillomavirus type 16 late regulatory elementSemantic proximity Read ↗

The Effect of Productive HPV16 Infection on Global Gene Expression of Cervical EpitheliumSemantic proximity Read ↗

Splicing Genomics Events in Cervical Cancer: Insights for Phenotypic Stratification and Biomarker Potency.Semantic proximity Read ↗

The splicing factor kinase, SR protein kinase 1 (SRPK1) is essential for late events in the human papillomavirus life cycleSemantic proximity Read ↗

Control of human papillomavirus gene expression by alternative splicingSemantic proximity Read ↗

Virus-host interaction: investigating novel transcription factors involved in coupling HPV life cycle and epithelial differentiationSemantic proximity Read ↗

E6AP is important for HPV E6’s role in regulating epithelial homeostasis and its loss impairs keratinocyte commitment to differentiationSemantic proximity Read ↗

Alternative splicing in the genome of HPV and its regulationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.