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Article

Hyper-IgE syndrome.

Current opinion in immunology - 1 Oct 2009

Minegishi Yoshiyuki

Abstract excerpt

Hyper-IgE syndrome (HIES) is a complex primary immunodeficiency characterized by atopic dermatitis associated with extremely high serum IgE levels and susceptibility to infections with extracellular bacteria. Nonimmunological abnormalities, including a distinctive facial appearance, fracture following minor trauma, scoliosis, hyperextensive joints, and the retention of deciduous teeth are also observed in most...

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Source

Identifiers

PMID: 19717292
DOI: 10.1016/j.coi.2009.07.013

Genes

STAT3
TYK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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