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Article

Genetic origins of hyper-IgE syndrome.

Current allergy and asthma reports - 1 Sept 2008

Minegishi Yoshiyuki, Karasuyama Hajime

Abstract excerpt

Hyper-IgE syndrome (HIES) is a complex primary immunodeficiency characterized by high serum IgE, chronic eczematoid dermatitis, and recurrent extracellular bacterial infections. Two types of HIES have been reported: type 1 and type 2. Type 1 HIES displays abnormalities in multiple systems, including the skeletal, dental, and immune systems, whereas type 2 shows abnormalities confined to the immune system. We...

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Identifiers

PMID: 18682102
DOI: 10.1007/s11882-008-0075-x

Genes

STAT3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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