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Article

Hyper IgE syndrome: an update on clinical aspects and the role of signal transducer and activator of transcription 3.

Current opinion in allergy and clinical immunology - 1 Dec 2008

Paulson Michelle L, Freeman Alexandra F, Holland Steven M

Abstract excerpt

PURPOSE OF REVIEW: Hyper IgE syndrome (HIES) is a primary immunodeficiency characterized by eczema, recurrent skin and lung infections, elevated serum IgE, and connective tissue and skeletal abnormalities. We present newly recognized aspects of the clinical phenotype and discuss recent genetic and immunologic findings. RECENT FINDINGS: In 2007, mutations in signal transducer and activator of transcription 3...

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Source

Identifiers

PMID: 18978467
DOI: 10.1097/ACI.0b013e3283184210

Genes

STAT3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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