Article
Rheumatoid arthritis does not share most of the newly identified systemic lupus erythematosus genetic factors.
Arthritis and rheumatism - 1 Sept 2009
Suarez-Gestal Marian, Calaza Manuel, Dieguez-Gonzalez Rebeca, Perez-Pampin Eva, Pablos Jose Luis, Navarro Federico, Narvaez Javier, Marenco Jose Luis, Herrero-Beaumont Gabriel, Fernandez-Gutierrez Benjamin, Lamas Jose Ramon, de la Serna Arturo Rodriguez, Ortiz Ana Maria, Carreño Luis, Cañete Juan D, Caliz Rafael, Blanco Francisco J, Balsa Alejandro, Gomez-Reino Juan J, Gonzalez Antonio
Abstract excerpt
OBJECTIVE: Rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) share some genetic factors such as HLA, PTPN22, STAT4, and 6q23. The aim of this study was to determine whether 9 other SLE genetic factors are also implicated in RA susceptibility. METHODS: A characteristic single-nucleotide polymorphism (SNP) in each of 9 genetic factors, ITGAM (rs1143679), C8orf13-BLK (rs13277113), TYK2 (rs2304256),...
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