Article
Association between beta2-glycoprotein I plasma levels and the risk of myocardial infarction in older men.
Blood - 22 Oct 2009
de Laat Bas, de Groot Philip G, Derksen Ronald H W M, Urbanus Rolf T, Mertens Koen, Rosendaal Frits R, Doggen Carine J M
Abstract excerpt
von Willebrand factor (VWF) serves as adhesive surface for platelets to adhere to the vessel wall. We have recently found that beta2-glycoprotein I is able to inhibit platelet binding to VWF, indicating a role in the pathophysiology of arterial thrombosis. In the present study, we investigated whether differences in beta2-glycoprotein I plasma levels influence the risk of myocardial infarction. We have measured...
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