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Article

Platelet GPIbalpha, GPIV and vWF polymorphisms and fatal pre-hospital MI among middle-aged men.

Journal of thrombosis and thrombolysis - 1 Oct 2008

Pellikka Minna, Narhi Lassi, Perola Markus, Penttila Antti, Karhunen Pekka J, Mikkelsson Jussi

Abstract excerpt

BACKGROUND: The binding of platelet glycoprotein (GP) Ib-IX-V receptor complex to subendothelial collagen via von Willebrand factor is the initial step of the formation of platelet thrombi following atherosclerotic plaque rupture. Platelet GPIV binds to collagen and/or thrombospondin and further activates platelets. Genetic variation in these proteins could associate with platelet aggregability and the risk of...

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Source

Identifiers

PMID: 17619827
DOI: 10.1007/s11239-007-0072-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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