Article
Lipoprotein(a) and the significance of the association between platelet glycoprotein IIIa polymorphisms and the risk of premature myocardial infarction.
Atherosclerosis - 1 Sept 1998
Joven J, Simó J M, Vilella E, Camps J, Masana L, de Febrer G, Camprubí M, Richart C, Bardaji A, Casao E, Pocovi M, Civeira F
Abstract excerpt
Platelet glycoprotein IIb/IIIa may be involved in the pathogenesis of myocardial infarction as the key element in platelet aggregation and as the binding site of lipoprotein(a) to platelets, inhibiting plasminogen binding and activation. Recently, a strong association between the P1A2 polymorphis...
Topics
- Adult
- Alleles
- Apolipoproteins E
- Female
- Gene Frequency
- Genotype
- Humans
- Lipoprotein(a)
- Male
- Middle Aged
- Myocardial Infarction
- Platelet Glycoprotein GPIIb-IIIa Complex
- Polymorphism, Genetic
- Risk Factors