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Article

Conserved domains and structure prediction of human cytomegalovirus UL27 protein.

Antiviral therapy - 1 Jan 2009

Hantz Sébastien, Couvreux Anthony, Champier Gaël, Trapes Laurène, Cotin Sébastien, Denis François, Bouaziz Serge, Alain Sophie

Abstract excerpt

BACKGROUND: The human cytomegalovirus (HCMV) nuclear UL27 protein (pUL27) could be involved at the stage of nuclear egress. Maribavir is a new anti-HCMV drug that targets nuclear egress through direct inhibition of the HCMV serine-threonine kinase, UL97 protein (pUL97). Because maribavir-resistance-related mutations are observed in both proteins, pUL27 is thought to interfere with pUL97 activity; however, its...

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PMID: 19704169

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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