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Article

Human immunodeficiency virus type 1 recombinant reverse transcriptase enzymes containing the G190A and Y181C resistance mutations remain sensitive to etravirine.

Antimicrobial agents and chemotherapy - 1 Nov 2009

Xu Hongtao, Quan Yudong, Brenner Bluma G, Bar-Magen Tamara, Oliveira Maureen, Schader Susan M, Wainberg Mark A

Abstract excerpt

Etravirine (ETR) is a second-generation nonnucleoside reverse transcriptase (RT) inhibitor (NNRTI) active against common human immunodeficiency virus type 1 (HIV-1) drug-resistant strains. This study was designed to determine the extent to which each of the Y181C or G190A mutations in RT might confer resistance to ETR and other members of the NNRTI family of drugs. Recombinant HIV-1 RT enzymes containing either...

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Identifiers

PMID: 19704127
DOI: 10.1128/AAC.00800-09
PMCID: PMC2772356

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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