Article
Porphyromonas gingivalis mutant defective in a putative extracytoplasmic function sigma factor shows a mutator phenotype.
Oral microbiology and immunology - 1 Oct 2009
Kikuchi Y, Ohara N, Ueda O, Hirai K, Shibata Y, Nakayama K, Fujimura S
Abstract excerpt
INTRODUCTION: Porphyromonas gingivalis is implicated as a major pathogen in the development and progression of chronic periodontitis. P. gingivalis must possess the ability to tolerate stress signals outside the cytoplasmic membrane by transcriptional activation of genes encoding proteins involved in defense or repair processes. Some bacteria utilize a distinct subfamily of sigma factors to regulate...
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