Article
A putative TetR regulator is involved in nitric oxide stress resistance in Porphyromonas gingivalis.
Molecular oral microbiology - 1 Aug 2016
Boutrin M-C, Yu Y, Wang C, Aruni W, Dou Y, Shi L, Fletcher H M
Abstract excerpt
To survive in the periodontal pocket, Porphyromonas gingivalis, the main causative agent of periodontal disease, must overcome oxidative and nitric oxide (NO) stress. Previously, we reported that, in the presence of NO comparable to stress conditions, the transcriptome of P. gingivalis was differentially expressed, and genes belonging to the PG1178-81 cluster were significantly upregulated. To further evaluate...
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