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Clonal structure and 21-year evolution of Streptococcus pneumoniae serotype 1 isolates in northern Spain.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases - 1 Sept 2009

Marimon J M, Ercibengoa M, Alonso M, Zubizarreta M, Pérez-Trallero E

Abstract excerpt

This study of 135 serotype 1 pneumococcal isolates (88 invasive and 47 non-invasive), collected between 1987 and 2007, gave eight sequence types (217, 227, 228, 304, 305, 306, 3860 and 3861) that group, using eBurst, into three different lineages and one singleton. The annual incidence of serotype 1 invasive episodes per million inhabitants increased from 1.8 in 1987-1993 to 4.0 in 1994-2000, and to 25.6 in...

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PMID: 19702591
DOI: 10.1111/j.1469-0691.2009.02883.x

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