Article
CFB/C2 gene polymorphisms and risk of age-related macular degeneration: a systematic review and meta-analysis.
Current eye research - 1 Apr 2012
Sun Chuan, Zhao Min, Li Xiaoxin
Abstract excerpt
PURPOSE: To investigate whether the polymorphisms of CFB/C2 gene are associated with age-related macular degeneration (AMD), and to evaluate the magnitude of gene effect. METHODS: We performed a meta-analysis of the association between four SNPs in CFB/C2 gene (rs9332739, rs547154, rs4151667, and rs641153) and risk of AMD using data from 15 case-control studies involving 8905 subjects. Pooled odds ratios (ORs)...
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