Article
Three members of the LC8/DYNLL family are required for outer arm dynein motor function.
Molecular biology of the cell - 1 Sept 2008
Tanner Christopher A, Rompolas Panteleimon, Patel-King Ramila S, Gorbatyuk Oksana, Wakabayashi Ken-ichi, Pazour Gregory J, King Stephen M
Abstract excerpt
The highly conserved LC8/DYNLL family proteins were originally identified in axonemal dyneins and subsequently found to function in multiple enzyme systems. Genomic analysis uncovered a third member (LC10) of this protein class in Chlamydomonas. The LC10 protein is extracted from flagellar axonemes with 0.6 M NaCl and cofractionates with the outer dynein arm in sucrose density gradients. Furthermore, LC10 is...
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