Article
Post-load insulin resistance does not predict virological response to treatment of chronic hepatitis C patients without the metabolic syndrome.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver - 1 May 2012
Fattovich Giovanna, Baroni Gianluca Svegliati, Pasino Michela, Pierantonelli Irene, Covolo Loredana, Ieluzzi Donatella, Passigato Nicola, Tonon Angelo, Faraci Maria Grazia, Guido Maria, Negro Francesco
Abstract excerpt
BACKGROUND AND AIM: The role of insulin resistance in predicting virological response to therapy of chronic hepatitis C is debated. We assessed the association between basal (defined as homeostasis model assessment of insulin resistance (HOMA-IR)>2) and post-load insulin resistance (as oral glucose insulin sensitivity index<9.8 mg/kg/min) with the rapid and sustained virological responses in chronic hepatitis C....
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