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Article

Reduced immunoglobulin class switch recombination in the absence of Artemis.

Blood - 22 Oct 2009

Rivera-Munoz Paola, Soulas-Sprauel Pauline, Le Guyader Gwenaël, Abramowski Vincent, Bruneau Sylvia, Fischer Alain, Pâques Frédéric, de Villartay Jean-Pierre

Abstract excerpt

Nonhomologous end-joining DNA repair factors, including Artemis, are all required for the repair of DNA double-strand breaks, which occur during the assembly of the variable antigen recognition domain of B-cell receptors and T-cell receptors through the V(D)J recombination. Mature B cells further shape their immunoglobulin repertoire on antigen recognition notably through the class switch recombination (CSR)...

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Share to DNA Breaks, Double-Stranded
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Enzyme-Linked Immunosorbent Assay

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Source

Identifiers

PMID: 19692705
DOI: 10.1182/blood-2008-11-188383

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Reduced immunoglobulin class switch recombination in the absence of Artemis.PMID 19692705Read ↗

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