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Article

Mice carrying a conditional Serca2(flox) allele for the generation of Ca(2+) handling-deficient mouse models.

Cell calcium - 1 Sept 2009

Andersson Kristin B, Finsen Alexandra V, Sjåland Cecilie, Winer Lisbeth H, Sjaastad Ivar, Odegaard Annlaug, Louch William E, Wang Yibin, Chen Ju, Chien Kenneth R, Sejersted Ole M, Christensen Geir

Abstract excerpt

Sarco(endo)plasmic reticulum calcium ATPases (SERCA) are cellular pumps that transport Ca(2+) into the sarcoplasmic reticulum (SR). Serca2 is the most widely expressed gene family member. The very early embryonic lethality of Serca2(null) mouse embryos has precluded further evaluation of loss of Serca2 function in the context of organ physiology. We have generated mice carrying a conditional Serca2(flox) allele...

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Identifiers

PMID: 19692123
DOI: 10.1016/j.ceca.2009.07.004
PMCID: PMC4313567

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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