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Article

The effect of hfq on global gene expression and virulence in Neisseria gonorrhoeae.

The FEBS journal - 1 Oct 2009

Dietrich Manuela, Munke Rebekka, Gottschald Marion, Ziska Elke, Boettcher Jan Peter, Mollenkopf Hans, Friedrich Alexandra

Abstract excerpt

Hfq is an RNA chaperone that functions as a pleiotropic regulator for RNA metabolism in bacteria. In several pathogenic bacteria, Hfq contributes indirectly to virulence by binding to riboregulators that modulate the stability or translation efficiency of RNA transcripts. To characterize the role of Hfq in the pathogenicity of Neisseria gonorrhoeae, we generated an N. gonorrhoeae hfq mutant. Infectivity and...

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Identifiers

PMID: 19691497
DOI: 10.1111/j.1742-4658.2009.07234.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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