Article
The RNA chaperone Hfq is important for growth and stress tolerance in Francisella novicida.
PloS one - 5 May 2011
Chambers Jacob R, Bender Kelly S
Abstract excerpt
The RNA-binding protein Hfq is recognized as an important regulatory factor in a variety of cellular processes, including stress resistance and pathogenesis. Hfq has been shown in several bacteria to interact with small regulatory RNAs and act as a post-transcriptional regulator of mRNA stability and translation. Here we examined the impact of Hfq on growth, stress tolerance, and gene expression in the...
Topics
- Adaptation, Physiological
- Amino Acid Sequence
- Biofilms
- DNA Transposable Elements
- Escherichia coli
- Francisella
- Gene Deletion
- Gene Expression Regulation, Bacterial
- Genes, Bacterial
- Genetic Complementation Test
- Host Factor 1 Protein