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The RyfA small RNA regulates oxidative and osmotic stress responses and virulence in uropathogenic Escherichia coli

27 May 2021

Abstract excerpt

Urinary tract infections (UTIs) are a common bacterial infectious disease in humans, and strains of uropathogenic Escherichia coli (UPEC) are the most frequent cause of UTIs. During infection, UPEC must cope with a variety of stressful conditions in the urinary tract. Here, we demonstrate that the small RNA (sRNA) RyfA of UPEC strains is required for resistance to oxidative and osmotic stresses. Transcriptomic...

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PMID: 34043736
DOI: 10.1371/journal.ppat.1009617

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