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Article

Identification of the methylator (serrated) colorectal cancer phenotype through precursor serrated polyps.

Diseases of the colon and rectum - 1 Sept 2009

Messick Craig A, Church James, Casey Graham, Kalady Matthew F

Abstract excerpt

PURPOSE: Colorectal cancers arise via cumulative genetic and molecular changes that cause mucosal instability, premalignant polyps, and malignant transformation. Distinct neoplastic pathways characterized by chromosomal instability, genetic mutation, and epigenetic methylation have been described, but their associated precursor polyps have not. This study analyzes characteristics of precursor polyps occurring...

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Identifiers

PMID: 19690479
DOI: 10.1007/DCR.0b013e3181afbe05

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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